Northern Region- The Northern Region of Guam is lightly populated and mostly owned by the U.S. Military. Cities like Dededo and Yigo are in this region. The Northern Region contains Ritidian Beach, one of the most isolated, beautiful beaches in Guam. The Northern Region is the least-visited by tourists.

Central/Metropolitan Region- The Central Region holds the majority of Guam's population and cities. A lot of shopping and restaurants are located in this area. This is the island's most visited area. This area contains most of Guam's cities and the island's international airport. It is prone to heavy traffic congestion. The Central Region is the most diverse. The population of the Central Region is approximately 120,000, and expected to grow to at least 140,000 by 2015.

Southern Region- Guam's Southern Region is mostly rural and picturesque. It is one of the most untouched and undeveloped areas on the island and the Chamorro culture is most preserved here. Cocos Island and the black sand beaches at Talofofo are popular places to visit in this region.